2-CYANO-3-PHENYLPYRIDINE synthesis

3synthesis methods

Product Name:2-CYANO-3-PHENYLPYRIDINE
CAS Number:39065-43-5
Molecular formula:C12H8N2
Molecular Weight:180.21

55758-02-6 Synthesis

55758-02-6
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98-80-6 Synthesis

98-80-6
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$5.00/5g

39065-43-5
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Yield:39065-43-5 73 %

Reaction Conditions:

Stage #1: 3-bromopyridine-2-carbonitrile;phenylboronic acidwith potassium carbonate;triphenylphosphine in water;Inert atmosphere;Suzuki-Miyaura Coupling;
Stage #2: with palladium diacetate in 1,2-dimethoxyethane;water;Inert atmosphere;Glovebox;Reflux;

References:

Vaid, Thomas P.;Cook, Monique E.;Scott, Jessica D.;Borjesson Carazo, Marino;Ruchti, Jonathan;Minteer, Shelley D.;Sigman, Matthew S.;McNeil, Anne J.;Sanford, Melanie S. [Chemistry - A European Journal,2022,vol. 28,# 70,art. no. E202202147]