![](/CAS/GIF/1878-49-5.gif)
(2-METHYLPHENOXY)ACETIC ACID synthesis
- Product Name:(2-METHYLPHENOXY)ACETIC ACID
- CAS Number:1878-49-5
- Molecular formula:C9H10O3
- Molecular Weight:166.17
![ETHYL (2-METHYLPHENOXY)ACETATE](/CAS/GIF/93917-68-1.gif)
93917-68-1
37 suppliers
$58.50/5g
![(2-METHYLPHENOXY)ACETIC ACID](/CAS/GIF/1878-49-5.gif)
1878-49-5
146 suppliers
$15.00/1g
Yield:1878-49-5 81%
Reaction Conditions:
with sodium hydroxide in ethanol;waterReflux;
Steps:
4 4.1.2.1 General synthetic procedure for phenoxyacetic acid analogues (4a-j)
General procedure: Compounds (3a-j,0.02mol) were dissolved in ethanol (15mL), sodium hydroxide (0.035mol) in water (5mL) was added, and the mixture was refluxed for 5-9h. The reaction mixture was cooled and acidified with 2N hydrochloric acid. The precipitate was filtered, washed with water, and finally recrystallized from methanol to afford desired compounds (4a-j). Compound (4a) is takenas a representative example to explain physical and characterization data.
References:
Mohammed, Yasser Hussein Eissa;Malojirao, Vikas H.;Thirusangu, Prabhu;Al-Ghorbani, Mohammed;Prabhakar;Khanum, Shaukath Ara [European Journal of Medicinal Chemistry,2018,vol. 143,p. 1826 - 1839]
![2-Methyl-4-chlorophenoxyacetic acid](/CAS/GIF/94-74-6.gif)
94-74-6
230 suppliers
$12.00/1 G
![(2-METHYLPHENOXY)ACETIC ACID](/CAS/GIF/1878-49-5.gif)
1878-49-5
146 suppliers
$15.00/1g
![Sodium chloroacetate](/CAS/GIF/3926-62-3.gif)
3926-62-3
260 suppliers
$16.69/250g
![o-Cresol](/CAS/GIF/95-48-7.gif)
95-48-7
432 suppliers
$17.00/25g
![(2-METHYLPHENOXY)ACETIC ACID](/CAS/GIF/1878-49-5.gif)
1878-49-5
146 suppliers
$15.00/1g