ChemicalBook CAS DataBase List (R)-N-(2-oxo-2-(pyrrolidin-3-ylaMino)-ethyl)-3-(trifluoroMethyl)benzaMide

(R)-N-(2-oxo-2-(pyrrolidin-3-ylaMino)-ethyl)-3-(trifluoroMethyl)benzaMide synthesis

3synthesis methods

Product Name:(R)-N-(2-oxo-2-(pyrrolidin-3-ylaMino)-ethyl)-3-(trifluoroMethyl)benzaMide
CAS Number:226249-16-7
Molecular formula:C14H16F3N3O2
Molecular Weight:315.29

226228-88-2 Synthesis

Benzamide, N-[2-oxo-2-[[(3R)-1-(phenylmethyl)-3-pyrrolidinyl]amino]ethyl]-3-(trifluoromethyl)-

226228-88-2
7 suppliers
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(R)-N-(2-oxo-2-(pyrrolidin-3-ylaMino)-ethyl)-3-(trifluoroMethyl)benzaMide

226249-16-7
9 suppliers
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Yield:226249-16-7 96%

Reaction Conditions:

with hydrogen;palladium(II) hydroxide in methanol at 20; under 2844.39 Torr;

References:

Xue, Chu-Biao;Feng, Hao;Cao, Ganfeng;Huang, Taisheng;Glenn, Joseph;Anand, Rajan;Meloni, David;Zhang, Ke;Kong, Lingquan;Wang, Anlai;Zhang, Yingxin;Zheng, Changsheng;Xia, Michael;Chen, Lihua;Tanaka, Hiroyuki;Han, Qi;Robinson;Modi, Dilip;Storace, Lou;Shao, Lixin;Sharief, Vaqar;Li, Mei;Galya, Laurine G.;Covington, Maryanne;Scherle, Peggy;Diamond, Sharon;Emm, Tom;Yeleswaram, Swamy;Contel, Nancy;Vaddi, Kris;Newton, Robert;Hollis, Greg;Friedman, Steven;Metcalf, Brian [ACS Medicinal Chemistry Letters,2011,vol. 2,# 6,p. 450 - 454] Location in patent:supporting information; experimental part

17794-48-8 Synthesis

2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid

17794-48-8
119 suppliers
$20.00/100mg

226249-16-7
9 suppliers
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References

2251-65-2 Synthesis

2251-65-2
212 suppliers
$10.00/1g

226249-16-7
9 suppliers
inquiry

References