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ChemicalBook CAS DataBase List Bis(2,2,6,6-tetramethyl-1-piperidinyloxy-4-yl) sebacate
2516-92-9

Bis(2,2,6,6-tetramethyl-1-piperidinyloxy-4-yl) sebacate synthesis

3synthesis methods
-

Yield:2516-92-9 96%

Reaction Conditions:

with dihydrogen peroxide in water;m-xylene at 30; pH=7.8; for 12 h;

Steps:

5 Method for preparing hindered amine nitroxide radical compound (sebacic acid dinitroxide radical-2,2,6,6-tetramethylpiperidinol ester) by basic heterogeneous catalysis system

Take 2g (4mmol) of sebacic acid diazoxide radical-2,2,6,6-tetramethylpiperidinol ester III into a 50mL two-necked round bottom flask, set up a thermometer sleeve, and add it to the reaction vessel 30mL meta-xylene was used as the reaction solvent to dissolve the compound shown in III. Maintain the reaction system at 30°C while continuously stirring. Use 0.05g/mL sodium carbonate aqueous solution to adjust the pH of the reaction system to 7.8, and slowly drop 2.4mL 30% (mass Concentration) Aqueous hydrogen peroxide (24 mmol). The reaction is carried out, TLC indicates the end point (about 12h), the reaction is stopped, the phases are separated, the organic phase is collected and dried with anhydrous sodium sulfate, the organic phase is concentrated to obtain 1.84g of the target product represented by formula VI as a red solid, with a yield of 96% , The purity is 97%.

References:

CN113429392,2021,A Location in patent:Paragraph 0054-0059

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