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174532-77-5

3-ForMyl Nevirapine synthesis

9synthesis methods
284686-20-0 Synthesis
N-[5-BroMo-2-(cyclopropylaMino)-4-Methyl-3-pyridinyl]-2-chloro-3-pyridinecarboxaMide

284686-20-0
9 suppliers
$70.00/2mg

-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: 92.7 percent / sodium hydride; pyridine / 0.5 h / Heating
2.1: 64.9 percent / tetrakis(triphenylphosphine)palladium / dimethylformamide / 1.5 h / 90 °C
3.1: ozone / methanol; CH2Cl2 / -78 °C
3.2: 47 percent / dimethyl sulfide / methanol; CH2Cl2

References:

Grozinger, Karl G.;Byrne, Denis P.;Nummy, Laurence J.;Ridges, Michael D.;Salvagno, Annette [Journal of Heterocyclic Chemistry,2000,vol. 37,# 2,p. 229 - 239]

284686-17-5 Synthesis
N-Cyclopropyl-4-Methyl-3-nitro-2-pyridinaMine

284686-17-5
7 suppliers
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