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3-ISOPROPOXY-4-METHOXYPHENYLBORONIC ACID synthesis

5synthesis methods
462092-23-5 Synthesis
4-BROMO-2-ISOPROPOXY-1-METHOXYBENZENE

462092-23-5
20 suppliers
$55.00/250mg

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Yield:516465-82-0 81%

Reaction Conditions:

Stage #1: 4-bromo-2-isopropoxy-1-methoxybenzenewith tert.-butyl lithium in tetrahydrofuran;pentane at -78; for 1 h;
Stage #2: with Trimethyl borate in tetrahydrofuran;pentane at -78 - 20;

References:

Fujikawa, Naotaka;Ohta, Takeshi;Yamaguchi, Tomohiro;Fukuda, Tsutomu;Ishibashi, Fumito;Iwao, Masatomo [Tetrahedron,2006,vol. 62,# 4,p. 594 - 604]

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