ChemicalBook CAS DataBase List 3-METHYL-2-BUTANOL

3-METHYL-2-BUTANOL synthesis

10synthesis methods

Product Name:3-METHYL-2-BUTANOL
CAS Number:598-75-4
Molecular formula:C5H12O
Molecular Weight:88.15

563-80-4
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$17.00/25mL

598-75-4
105 suppliers
$33.00/25mL

Yield:598-75-4 88%

Reaction Conditions:

with [(η6-p-cymene)ruthenium(II)Cl((C₅H₄N)-2-CHNC(CH₃)₃)](hexafluorophosphate);sodium hydroxide in isopropyl alcohol at 82; for 16 h;Catalytic behavior;Inert atmosphere;Schlenk technique;Reflux;

Steps:

General procedure: In a typical experiment, the ketone (8.5 mmol), ruthenium(II) complex (0.00425 mmol) and NaOH (3.4 mmol) in 10 mL of 2-propanol were introduced into a Schlenk tube fitted with a reflux condenser and heated to 82 °C in an inert atmosphere. The reaction was then monitored at various time intervals by the use of GC. This was achieved by taking an aliquot, which was first passed through a pad of silica, and then injected (0.1 lL) into the GC. The identity of the alcohol was confirmed by comparison with commercially available (Aldrich Chemical Co) pure samples.

References:

Gichumbi, Joel M.;Friedrich, Holger B.;Omondi, Bernard [Transition Metal Chemistry,2016,vol. 41,# 8,p. 867 - 877]

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5076-19-7 Synthesis