3-(methylamino)butan-1-ol synthesis
- Product Name:3-(methylamino)butan-1-ol
- CAS Number:2704-55-4
- Molecular formula:C5H13NO
- Molecular Weight:103.16
590-90-9
277 suppliers
$10.00/1g
74-89-5
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$13.44/25ML
2704-55-4
23 suppliers
$45.00/100mg
Yield:2704-55-4 87%
Reaction Conditions:
with palladium 10% on activated carbon in ethanol at 20; for 16 h;Inert atmosphere;
Steps:
14 14. Preparation of 3-(methylamino)butan-1-ol (Intermediate M2)
4-hydroxylbutan-2-one (3 g, 34 mmol) and methylamine (12.77 g, 68 mmol) were dissolved in ethanol (10 mL), and 10% palladium on carbon (300 mg) was added.
The mixture solution reacted at room temperature for 16 hrs.
The reaction solution was filtered, and the filtrate was concentrated to obtain 3-(methylamino)butan-1-ol (3 g, yield 87%), which was directly used in the next step.
References:
US2020/140431,2020,A1 Location in patent:Paragraph 0166; 0193-0194