3-Methylpiperidin-4-one hydrochloride synthesis
- Product Name:3-Methylpiperidin-4-one hydrochloride
- CAS Number:4629-78-1
- Molecular formula:C6H12ClNO
- Molecular Weight:149.62
181269-69-2
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4629-78-1
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Yield:-
Reaction Conditions:
with hydrogenchloride in ethanol;dichloromethane at 0 - 25;
Steps:
15.1
Step 1: To a solution of racemic 3-methyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester in anhydrous DCM at 0° C., ethanolic-HCl was added slowly and the reaction mixture was allowed to stir at 25° C. for 3 h. TLC (hexanes/EtOAc 40% EtOAc) showed complete consumption of the starting material. The reaction mixture was evaporated to give racemic 3-methyl-piperidin-4-one hydrochloride which was used crude in the next reaction.
References:
US2010/144745,2010,A1 Location in patent:Page/Page column 46
17038-84-5
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4629-78-1
6 suppliers
$11.00/250mg