![](/CAS/GIF/35219-13-7.gif)
4-(1,3,4-OXADIAZOL-2-YL)ANILINE synthesis
- Product Name:4-(1,3,4-OXADIAZOL-2-YL)ANILINE
- CAS Number:35219-13-7
- Molecular formula:C8H7N3O
- Molecular Weight:161.16
![Sodium chlorodifluoroacetate](/CAS/GIF/1895-39-2.gif)
1895-39-2
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5351-17-7
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$10.00/1g
![4-(1,3,4-OXADIAZOL-2-YL)ANILINE](/CAS/GIF/35219-13-7.gif)
35219-13-7
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$29.00/100mg
Yield:35219-13-7 81%
Reaction Conditions:
with potassium phosphate in acetonitrile at 100; for 1 h;Sealed tube;Inert atmosphere;
Steps:
2. General procedure for the synthesis of 3
General procedure: CH3CN (2 mL) was added to a mixture of ClCF2COONa 2a (0.3 mmol, 1.5 equiv) and hydrazides 1 (0.2 mmol, 1 equiv) in the presence of K3PO4 (0.3 mmol, 1.5 equiv). Then the sealed tube was stirred at 100 °C under N2 for 1 h. Upon completion of the reaction, the solvent was evaporated under reduced pressure and the residue was purified by flash column chromatograph (silica gel, petroleum ether:EtOAc = 2:1, v/v) to give the desired product 3.
References:
Wang, Ya;Mu, Shiqiang;Li, Xin;Song, Qiuling [Chinese Chemical Letters,2022,vol. 33,# 3,p. 1511 - 1514] Location in patent:supporting information
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4291-13-8
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![4-(1,3,4-OXADIAZOL-2-YL)ANILINE](/CAS/GIF/35219-13-7.gif)
35219-13-7
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$29.00/100mg
![2-(3-nitrophenyl)-1,3,4-oxadiazole](/CAS/GIF/5565-72-0.gif)
5565-72-0
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$212.00/1g
![4-(1,3,4-OXADIAZOL-2-YL)ANILINE](/CAS/GIF/35219-13-7.gif)
35219-13-7
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5378-35-8
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636-97-5
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![4-(1,3,4-OXADIAZOL-2-YL)ANILINE](/CAS/GIF/35219-13-7.gif)
35219-13-7
39 suppliers
$29.00/100mg