ChemicalBook CAS DataBase List 4-(4-bromophenyl)-4-hydroxycyclohexanone

4-(4-bromophenyl)-4-hydroxycyclohexanone synthesis

5synthesis methods

Product Name:4-(4-bromophenyl)-4-hydroxycyclohexanone
CAS Number:1477524-71-2
Molecular formula:C12H13BrO2
Molecular Weight:269.13

106-37-6 Synthesis

106-37-6
473 suppliers
$9.00/5g

637-88-7 Synthesis

637-88-7
309 suppliers
$5.00/1g

4-(4-bromophenyl)-4-hydroxycyclohexanone

1477524-71-2
12 suppliers
inquiry

Yield:1477524-71-2 92%

Reaction Conditions:

Stage #1: 1.4-dibromobenzenewith n-butyllithium in tetrahydrofuran;hexane at 0;Flow reactor;
Stage #2: 1,4-Cyclohexanedione in tetrahydrofuran;hexane at 0;Flow reactor;

References:

Kim, Heejin;Lee, Hyune-Jea;Kim, Dong-Pyo [Angewandte Chemie - International Edition,2016,vol. 55,# 4,p. 1422 - 1426][Angew. Chem.,2016,vol. 128,# 4,p. 1444 - 1448,5] Location in patent:supporting information

125962-59-6 Synthesis