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4-chloro-N,N,6-trimethylpyrimidin-2-amine synthesis
- Product Name:4-chloro-N,N,6-trimethylpyrimidin-2-amine
- CAS Number:5734-62-3
- Molecular formula:C7H10ClN3
- Molecular Weight:171.63
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5600-21-5
319 suppliers
$18.00/25g
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74-88-4
351 suppliers
$15.00/10g
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5734-62-3
25 suppliers
$45.00/100mg
Yield:5734-62-3 74 mg
Reaction Conditions:
Stage #1: 2-amino-6-methyl-4-chloropyrimidinewith sodium hydride in tetrahydrofuran at 0 - 20; for 0.0833333 h;
Stage #2: methyl iodide in tetrahydrofuran at 20; for 16 h;
References:
Henderson, Scott H.;Sorrell, Fiona;Bennett, James;Fedorov, Oleg;Hanley, Marcus T.;Godoi, Paulo H.;Ruela De Sousa, Roberta;Robinson, Sean;Ashall-Kelly, Alexander;Hopkins Navratilova, Iva;Walter, Daryl S.;Elkins, Jonathan M.;Ward, Simon E. [Journal of Medicinal Chemistry,2021,vol. 64,# 15,p. 11709 - 11728] Location in patent:supporting information
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5424-21-5
330 suppliers
$10.00/5g
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124-40-3
522 suppliers
$18.00/100ml
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535-89-7
2 suppliers
$66.59/250mg
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5734-62-3
25 suppliers
$45.00/100mg
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19810-73-2
10 suppliers
inquiry
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5734-62-3
25 suppliers
$45.00/100mg