5-(4-Methoxyphenyl)-4H-1,2,4-triazol-3-amine synthesis

6synthesis methods

Product Name:5-(4-Methoxyphenyl)-4H-1,2,4-triazol-3-amine
CAS Number:54464-14-1
Molecular formula:C9H10N4O
Molecular Weight:190.2

420-04-2 Synthesis

420-04-2
339 suppliers
$15.00/25g

874-90-8 Synthesis

874-90-8
344 suppliers
$8.00/10g

5-(4-Methoxyphenyl)-4H-1,2,4-triazol-3-amine

54464-14-1
29 suppliers
$98.00/1g

Yield:54464-14-1 92%

Reaction Conditions:

Stage #1: CYANAMIDwith hydroxylamine hydrochloride;triethylamine in ethanol at 100; for 12 h;Inert atmosphere;Schlenk technique;
Stage #2: 4-methoxybenzonitrilewith iron(III) chloride;potassium carbonate in ethanol;dimethyl sulfoxide at 100; for 12 h;Sealed tube;Inert atmosphere;Schlenk technique;

References:

Rohand, Taoufik;Mkpenie, Victor N.;El Haddad, Mohammadine;Markó, István E. [Journal of Heterocyclic Chemistry,2019,vol. 56,# 2,p. 690 - 695]

420-04-2 Synthesis

420-04-2
339 suppliers
$15.00/25g