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4-OXO-3,4-DIHYDRO-PHTHALAZINE-1-CARBOXYLIC ACID METHYL ESTER synthesis

4synthesis methods
-

Yield:53960-10-4 64%

Reaction Conditions:

with sodium hydrogencarbonate in N,N-dimethyl-formamide at 23; for 16 h;Inert atmosphere;

References:

Mood, Aaron D.;Premachandra, Ilandari Dewage Udara Anulal;Hiew, Stanley;Wang, Fuqiang;Scott, Kevin A.;Oldenhuis, Nathan J.;Liu, Haoping;Van Vranken, David L. [ACS Medicinal Chemistry Letters,2017,vol. 8,# 2,p. 168 - 173] Location in patent:supporting information