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ChemicalBook CAS DataBase List 6-phenyl-3,4-dihydroisoquinolin-1(2H)-one
1309955-14-3

6-phenyl-3,4-dihydroisoquinolin-1(2H)-one synthesis

2synthesis methods
147497-32-3 Synthesis
6-BROMO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE

147497-32-3
148 suppliers
$14.00/100mg

6-phenyl-3,4-dihydroisoquinolin-1(2H)-one

1309955-14-3
8 suppliers
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Yield:1309955-14-3 80%

Reaction Conditions:

with tetrabutylammomium bromide;palladium diacetate;potassium carbonate in water at 95; for 3 h;Inert atmosphere;Sealed tube;Suzuki-Miyaura Coupling;

References:

Morgan, Rory K.;Kirby, Ilsa T.;Vermehren-Schmaedick, Anke;Rodriguez, Kelsie;Cohen, Michael S. [ACS Medicinal Chemistry Letters,2019,vol. 10,# 1,p. 74 - 79] Location in patent:supporting information