ChemicalBook CAS DataBase List ETHYL 4-CHLORO-5-ISOPROPYLPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE

ETHYL 4-CHLORO-5-ISOPROPYLPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE synthesis

7synthesis methods

Product Name:ETHYL 4-CHLORO-5-ISOPROPYLPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE
CAS Number:658084-80-1
Molecular formula:C12H14ClN3O2
Molecular Weight:267.71

651744-40-0 Synthesis

ETHYL 5-ISOPROPYL-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE

651744-40-0
28 suppliers
$154.00/250mg

ETHYL 4-CHLORO-5-ISOPROPYLPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE

658084-80-1
35 suppliers
$360.00/250mg

Yield:658084-80-1 90%

Reaction Conditions:

with trichlorophosphate at 110; for 3 h;

Steps:

2 Example 2; [4-CHLORO- [2, 1-F] [1,] 2,4] [TRIAZIN-5- (1-METHYLETHYL) PYRROLO-6-CARBOXYLIC] acid ethyl ester

A solution of Example 1 (1 g) in phosphorous oxychloride (5 ml) was heated at [110 °C] for 3 h. The mixture was cooled and concentrated in vacuo to afford the title compound (90% yield) as an oil. [LC/MS] ; (M+H) + = 268.7. The compound was used without further purification.

References:

WO2004/13145,2004,A1 Location in patent:Page 30

651744-40-0 Synthesis

651744-40-0
28 suppliers
$154.00/250mg

658084-80-1
35 suppliers
$360.00/250mg

References

651744-38-6 Synthesis