7-Chloroquinolin-4-ol synthesis
- Product Name:7-Chloroquinolin-4-ol
- CAS Number:86-99-7
- Molecular formula:C9H6ClNO
- Molecular Weight:179.6
86-47-5
100 suppliers
$50.00/100mg
86-99-7
181 suppliers
$12.00/5g
Yield:86-99-7 98.5%
Reaction Conditions:
in paraffin oil at 230; for 0.833333 h;Temperature;Solvent;
Steps:
1-3 Synthesis of hydroxy-7-chloroquinoline (8) (decarboxylation)
Add 120mL of paraffin oil to the reaction vessel and add it in batches when the temperature reaches 23040g of 7-chloro-4-hydroxyquinoline-2-carboxylic acid, continue to react for 50 minutes at this temperature after the addition is complete,It was filtered when the temperature dropped to 30°C, and the filter cake was washed and dried with petroleum ether to obtain 31.6 g of product, with a yield of 98.5%. Melting point 276-279°C.
References:
CN111362872,2020,A Location in patent:Paragraph 0020; 0025-0026; 0029; 0034-0035; 0038; 0043-0044
86-98-6
484 suppliers
$10.00/10g
86-99-7
181 suppliers
$12.00/5g
![diethyl [(m-chloroanilino)methylene]malonate](/CAS/GIF/3412-99-5.gif)
3412-99-5
21 suppliers
inquiry
86-99-7
181 suppliers
$12.00/5g
86-98-6
484 suppliers
$10.00/10g
91-22-5
383 suppliers
$10.00/25g
612-61-3
123 suppliers
$5.00/100mg
86-99-7
181 suppliers
$12.00/5g
26707-52-8
11 suppliers
inquiry
86-99-7
181 suppliers
$12.00/5g