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ChemicalBook CAS DataBase List 1-METHYL-3-(2-METHYLPROPYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID

1-METHYL-3-(2-METHYLPROPYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: hydrazine hydrate / ethanol / 1 h / 0 °C
2: N,N-dimethyl-formamide / 3 h / 60 °C
3: sodium hydroxide / water; tetrahydrofuran / 2 h / 70 °C

References:

Si, Wei-Jie;Wang, Xiao-Bin;Chen, Min;Wang, Meng-Qi;Lu, Ai-Min;Yang, Chun-Long [New Journal of Chemistry,2019,vol. 43,# 7,p. 3000 - 3010]

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