methyl 5-(aminomethyl)-2-chlorobenzoate hydrochloride synthesis
- Product Name:methyl 5-(aminomethyl)-2-chlorobenzoate hydrochloride
- CAS Number:90942-47-5
- Molecular formula:C9H11Cl2NO2
- Molecular Weight:236.0951
118-91-2
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90942-47-5
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Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: sulfuric acid / 16 h / 22 - 26 °C
2.1: hydrogenchloride / water; 1,4-dioxane / 12 h / Reflux
2.2: 16 h / 0 - 26 °C
3.1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 22 - 26 °C
4.1: hydrogenchloride / ethyl acetate / 2 h / 22 - 26 °C
References:
GLENMARK PHARMACEUTICALS S.A.;GHARAT, Laxmikant Atmaram;BANERJEE, Abhisek;KHAIRATKAR-JOSHI, Neelima;KATTIGE, Vidya Ganapati WO2013/72825, 2013, A1
![Benzoic acid, 2-chloro-5-[[(2,2,2-trifluoroacetyl)amino]methyl]-](/CAS/20210111/GIF/1294496-57-3.gif)
1294496-57-3
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90942-47-5
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165950-04-9
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90434-27-8
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90942-47-5
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