tert-Butyl 6-aMino-7-fluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate synthesis

9synthesis methods

Product Name:tert-Butyl 6-aMino-7-fluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS Number:912846-68-5
Molecular formula:C14H19FN2O2
Molecular Weight:266.31

912846-67-4 Synthesis

tert-Butyl 7-fluoro-6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate

912846-67-4
31 suppliers
$70.00/100mg

tert-Butyl 6-aMino-7-fluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate

912846-68-5
30 suppliers
$238.50/250mg

Yield:912846-68-5 100%

Reaction Conditions:

with palladium on carbon;hydrogen in ethanol at 20;

References:

Watson, Nigel S.;Adams, Carl;Belton, David;Brown, David;Burns-Kurtis, Cynthia L.;Chaudry, Laiq;Chan, Chuen;Convery, Máire A.;Davies, David E.;Exall, Anne M.;Harling, John D.;Irvine, Stephanie;Irving, Wendy R.;Kleanthous, Savvas;McLay, Iain M.;Pateman, Anthony J.;Patikis, Angela N.;Roethke, Theresa J.;Senger, Stefan;Stelman, Gary J.;Toomey, John R.;West, Robert I.;Whittaker, Caroline;Zhou, Ping;Young, Robert J. [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 6,p. 1588 - 1592] Location in patent:scheme or table

912846-63-0 Synthesis

2,2,2-Trifluoro-N-[2-(4-fluorophenyl)-ethyl]acetamide

912846-63-0
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912846-68-5
30 suppliers
$238.50/250mg

References

Ethanone, 2,2,2-trifluoro-1-(7-fluoro-3,4-dihydro-6-nitro-2(1H)-isoquinolinyl)-

912846-65-2
2 suppliers
inquiry

912846-68-5
30 suppliers
$238.50/250mg

References

2,2,2-trifluoro-1-(7-fluoro-3,4-dihydro-1H-isoquinolin-2-yl)ethanone

912846-64-1
4 suppliers
inquiry

912846-68-5
30 suppliers
$238.50/250mg

References

1583-88-6
143 suppliers
$18.32/25g

912846-68-5
30 suppliers
$238.50/250mg

References