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Benzene, 1-fluoro-4-[2-(4-methoxyphenyl)ethyl]- synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 20 °C / Inert atmosphere; Schlenk technique
2: copper(l) iodide; bis-diphenylphosphinomethane; lithium methanolate; magnesium / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere; Schlenk technique

References:

Liu, Jing-Hui;Yang, Chu-Ting;Lu, Xiao-Yu;Zhang, Zhen-Qi;Xu, Ling;Cui, Mian;Lu, Xi;Xiao, Bin;Fu, Yao;Liu, Lei [Chemistry - A European Journal,2014,vol. 20,# 47,p. 15334 - 15338]