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ChemicalBook CAS DataBase List ETHYL 2,6-DIMETHYLBENZOYLFORMATE
698392-47-1

ETHYL 2,6-DIMETHYLBENZOYLFORMATE synthesis

4synthesis methods
6781-98-2 Synthesis
2-Chloro-1,3-dimethylbenzene

6781-98-2
159 suppliers
$9.00/5g

4755-77-5 Synthesis
Ethyl chlorooxoacetate

4755-77-5
334 suppliers
$9.00/25g

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Yield:698392-47-1 99%

Reaction Conditions:

Stage #1: 2,6-dimethyl-1-chlorobenzenewith lithium in diethyl ether at 3 - 6;
Stage #2: with copper(l) cyanide in tetrahydrofuran;diethyl ether at -80 - -25; for 0.416667 h;
Stage #3: Ethyl oxalyl chloride in tetrahydrofuran;diethyl ether at -80;

References:

Screttas, Constantinos G.;Steele, Barry R.;Micha-Screttas, Maria;Heropoulos, Georgios A. [Organic Letters,2012,vol. 14,# 22,p. 5680 - 5683] Location in patent:supporting information

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