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ChemicalBook CAS DataBase List GZD 824
1257628-77-5

GZD 824 synthesis

4synthesis methods
694499-26-8 Synthesis
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline

694499-26-8
229 suppliers
$9.00/250mg

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium tert-butylate / tetrahydrofuran / 3 h / -20 - 20 °C / Inert atmosphere
2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / acetonitrile / 20 h / 20 - 100 °C / Sealed tube; Inert atmosphere

References:

Ren, Xiaomei;Pan, Xiaofen;Zhang, Zhang;Wang, Deping;Lu, Xiaoyun;Li, Yupeng;Wen, Donghai;Long, Huoyou;Luo, Jinfeng;Feng, Yubing;Zhuang, Xiaoxi;Zhang, Fengxiang;Liu, Jianqi;Leng, Fang;Lang, Xingfen;Bai, Yang;She, Miaoqin;Tu, Zhengchao;Pan, Jingxuan;Ding, Ke [Journal of Medicinal Chemistry,2013,vol. 56,# 3,p. 879 - 894]

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