ChemicalBook CAS DataBase List LMI070

LMI070 synthesis

4synthesis methods

Product Name:LMI070
CAS Number:1562338-42-4
Molecular formula:C22H27N5O2
Molecular Weight:393.48

13659-23-9
179 suppliers
$19.00/1g

1562338-42-4
63 suppliers
$35.00/1mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1: potassium acetate; bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 24 h / 90 - 95 °C / Inert atmosphere
2: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane; water / 90 °C / Inert atmosphere
3: caesium carbonate; chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) / 1,4-dioxane; water / 90 °C / Inert atmosphere
4: hydrogenchloride / water

References:

Cheung, Atwood K.;Hurley, Brian;Kerrigan, Ryan;Shu, Lei;Chin, Donovan N.;Shen, Yiping;O'Brien, Gary;Sung, Moo Je;Hou, Ying;Axford, Jake;Cody, Emma;Sun, Robert;Fazal, Aleem;Fridrich, Cary;Sanchez, Carina C.;Tomlinson, Ronald C.;Jain, Monish;Deng, Lin;Hoffmaster, Keith;Song, Cheng;Van Hoosear, Mailin;Shin, Youngah;Servais, Rebecca;Towler, Christopher;Hild, Marc;Curtis, Daniel;Dietrich, William F.;Hamann, Lawrence G.;Briner, Karin;Chen, Karen S.;Kobayashi, Dione;Sivasankaran, Rajeev;Dales, Natalie A. [Journal of Medicinal Chemistry,2018,vol. 61,# 24,p. 11021 - 11036]

2403-88-5 Synthesis

2403-88-5
351 suppliers
$5.00/10g

1562338-42-4
63 suppliers
$35.00/1mg

References

3-chloro-6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazine

1562338-69-5
22 suppliers
inquiry

1562338-42-4
63 suppliers
$35.00/1mg

References

5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

1377503-12-2
62 suppliers
$49.00/100mg

1562338-42-4
63 suppliers
$35.00/1mg

References