ChemicalBook CAS DataBase List METHYL 3,5-DIMETHYLBENZOATE

METHYL 3,5-DIMETHYLBENZOATE synthesis

13synthesis methods

Product Name:METHYL 3,5-DIMETHYLBENZOATE
CAS Number:25081-39-4
Molecular formula:C10H12O2
Molecular Weight:164.2

499-06-9 Synthesis

499-06-9
373 suppliers
$6.00/10g

25081-39-4
105 suppliers
$6.00/250mg

Yield: 90%

Reaction Conditions:

with sulfuric acid in methanol

Steps:

1 Preparation of methyl-3,5-dimethyl-benzoate
Example 1 Preparation of methyl-3,5-dimethyl-benzoate A solution of 3,5-dimethyl benzoic acid (25 g, 0.17 mol) in methanol (250 ml) was treated with sulfuric acid (1 ml, cat. amount) and heated to reflux. After 10 hours, the solution was cooled to room temperature, concentrated to approximately 1/2 volume and poured into 200 ml of crushed ice. The mixture was extracted twice with 200 ml portions of diethyl ether. The organic phase was extracted with saturated aqueous sodium carbonate, dried over magnesium sulfate, and concentrated under reduced pressure. The resulting solid was recrystallized from hexanes to yield the product (24.5 g, 90% yield) as volatile white plates. mp=32°-35° C. (lit. mp=35°-36° C.)

References:

The Trustees of Columbia University in the City of New York US5342934, 1994, A

499-06-9 Synthesis

499-06-9
373 suppliers
$6.00/10g

67-56-1 Synthesis