![](/CAS/GIF/697739-03-0.gif)
Methyl 5-fluoro-2-methyl-3-nitrobenzoate synthesis
- Product Name:Methyl 5-fluoro-2-methyl-3-nitrobenzoate
- CAS Number:697739-03-0
- Molecular formula:C9H8FNO4
- Molecular Weight:213.16
![Methanol](/CAS/GIF/67-56-1.gif)
67-56-1
739 suppliers
$9.00/25ml
![5-Fluoro-2-Methyl-3-nitrobenzoic acid](/CAS/GIF/850462-64-5.gif)
850462-64-5
98 suppliers
$11.00/250mg
![Methyl 5-fluoro-2-methyl-3-nitrobenzoate](/CAS/GIF/697739-03-0.gif)
697739-03-0
160 suppliers
$8.00/250mg
Yield:697739-03-0 96%
Reaction Conditions:
with thionyl chloride for 3 h;Cooling with ice;Reflux;
Steps:
2.212.1 Step 1
Dissolve 5-fluoro-2-methyl-3-nitrobenzoic acid in 20ml of methanol, add dichlorosulfoxide (728ul, 10.04mmol) under ice bath, warm to reflux for 3h, after the reaction is complete, Spin dry, dilute with ethyl acetate, wash with saturated sodium bicarbonate and saturated sodium chloride respectively, and dry to obtain the target product 1.025g, yield 96%.
References:
CN110963994,2020,A Location in patent:Paragraph 0475; 1148-1150
![5-Fluoro-2-Methyl-3-nitrobenzoic acid](/CAS/GIF/850462-64-5.gif)
850462-64-5
98 suppliers
$11.00/250mg
![Iodomethane](/CAS/GIF/74-88-4.gif)
74-88-4
340 suppliers
$15.00/10g
![Methyl 5-fluoro-2-methyl-3-nitrobenzoate](/CAS/GIF/697739-03-0.gif)
697739-03-0
160 suppliers
$8.00/250mg
![5-Fluoro-2-Methyl-3-nitrobenzoic acid](/CAS/GIF/850462-64-5.gif)
850462-64-5
98 suppliers
$11.00/250mg
![Methyl 5-fluoro-2-methyl-3-nitrobenzoate](/CAS/GIF/697739-03-0.gif)
697739-03-0
160 suppliers
$8.00/250mg
![Methanol](/CAS/GIF/67-56-1.gif)
67-56-1
739 suppliers
$9.00/25ml
![5-Fluoro-2-methylbenzoic acid](/CAS/GIF/33184-16-6.gif)
33184-16-6
314 suppliers
$6.00/1g
![Methyl 5-fluoro-2-methyl-3-nitrobenzoate](/CAS/GIF/697739-03-0.gif)
697739-03-0
160 suppliers
$8.00/250mg
![METHYL 2-METHYL-5-FLUOROBENZOATE](/CAS/GIF/175278-29-2.gif)
175278-29-2
119 suppliers
$9.00/1g
![Methyl 5-fluoro-2-methyl-3-nitrobenzoate](/CAS/GIF/697739-03-0.gif)
697739-03-0
160 suppliers
$8.00/250mg