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ChemicalBook CAS DataBase List ML277
1401242-74-7

ML277 synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C
2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
3: triethylamine / dichloromethane / 20 °C

References:

Mattmann, Margrith E.;Yu, Haibo;Lin, Zhihong;Xu, Kaiping;Huang, Xiaofang;Long, Shunyou;Wu, Meng;McManus, Owen B.;Engers, Darren W.;Le, Uyen M.;Li, Min;Lindsley, Craig W.;Hopkins, Corey R. [Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,# 18,p. 5936 - 5941]

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