ChemicalBook CAS DataBase List [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone synthesis

5synthesis methods

Product Name:[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
CAS Number:1360705-96-9
Molecular formula:C22H20Cl2N4O4
Molecular Weight:475.32

960225-75-6 Synthesis

5-METHYL-4-NITRO-3-ISOXAZOLECARBOXYLIC ACID

960225-75-6
53 suppliers
$37.00/100mg

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

1360705-96-9
48 suppliers
$28.00/1mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 20 °C / Inert atmosphere
2: triethylamine / dichloromethane / 2 h / 20 °C

References:

We?wer, Michel;Bittker, Joshua A.;Lewis, Timothy A.;Shimada, Kenichi;Yang, Wan Seok;MacPherson, Lawrence;Dandapani, Sivaraman;Palmer, Michelle;Stockwell, Brent R.;Schreiber, Stuart L.;Munoz, Benito [Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,# 4,p. 1822 - 1826]