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ChemicalBook >> CAS DataBase List >> [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone price.
  • $32 - $2171
  • Product name: [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
  • CAS: 1360705-96-9
  • MF: C22H20Cl2N4O4
  • MW: 475.32
  • EINECS:
  • MDL Number:MFCD22666407
  • Synonyms:[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone;CID 49766530;ML 210;[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone;ML 210 - CID 49766530;Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-;ML 210 >=98% (HPLC);(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone
22 prices
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Brand
  • AK Scientific
  • Ambeed
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 5mg
  • 10
  • 1mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3040DH
  • Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
  • Packaging10mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3040DH
  • Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
  • Packaging50mg
  • Price$498
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging5mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging100mg
  • Price$473
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging250mg
  • Price$977
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging1g
  • Price$2171
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2017
  • Product descriptionML210-CID49766530 100%
  • Packaging10mg
  • Price$126.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546193
  • Product descriptionML 210 >98%
  • Packaging10mg
  • Price$198.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546193
  • Product descriptionML 210 >98%
  • Packaging50mg
  • Price$513.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBM170835
  • Product descriptionML 210
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberBM170835
  • Product descriptionML 210
  • Packaging50mg
  • Price$332.5
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number23282
  • Product descriptionML 210 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23282
  • Product descriptionML 210 ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23282
  • Product descriptionML 210 ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23282
  • Product descriptionML 210 ≥98%
  • Packaging25mg
  • Price$449
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0017911
  • Product descriptionML 210 99.92%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3040DH [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone 10mg $178 2021-12-16 Buy
AK Scientific 3040DH [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone 50mg $498 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 5mg $69 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 100mg $473 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 250mg $977 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 1g $2171 2021-12-16 Buy
Axon Medchem Axon2017 ML210-CID49766530 100% 10mg $126.5 2021-12-16 Buy
Biorbyt Ltd orb546193 ML 210 >98% 10mg $198.9 2021-12-16 Buy
Biorbyt Ltd orb546193 ML 210 >98% 50mg $513.4 2021-12-16 Buy
Biosynth Carbosynth BM170835 ML 210 10mg $95 2021-12-16 Buy
Biosynth Carbosynth BM170835 ML 210 50mg $332.5 2021-12-16 Buy
Cayman Chemical 23282 ML 210 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 23282 ML 210 ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 23282 ML 210 ≥98% 10mg $214 2024-03-01 Buy
Cayman Chemical 23282 ML 210 ≥98% 25mg $449 2024-03-01 Buy
ChemScene CS-0017911 ML 210 99.92% 5mg $90 2021-12-16 Buy

Properties

Boiling point :644.7±55.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ML210 (CAS 1360705-96-9) is selectively synthetic lethal to HRAS expressing cells compared to isogenic non-HRAS cells (IC50?= 7.1 nM for BJeLR (expressing HRASg12v) cells vs IC50?= 272 nM for BJeH-LT (non-HRAS expressing) cells.1?ML210 is able to inhibit glutathione peroxidase 4 (GPX4), an important selenoenzyme that protects cells from ferroptosis caused by iron catalyzed formation of free radicals from lipid peroxides.2,3?Treatment of several treatment-resistant cancer cell lines exhibiting a high mesenchymal state with ML210 resulted in selective induction of ferroptosis.3

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