N-(2-methoxyethyl)-2-nitrobenzenamine synthesis
- Product Name:N-(2-methoxyethyl)-2-nitrobenzenamine
- CAS Number:56436-24-9
- Molecular formula:C9H12N2O3
- Molecular Weight:196.2
1493-27-2
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$5.00/10g
109-85-3
264 suppliers
$10.00/1g
56436-24-9
8 suppliers
$309.00/1g
Yield:56436-24-9 100%
Reaction Conditions:
with N-ethyl-N,N-diisopropylamine in ethanol at 150; for 0.316667 h;Sealed vial;
Steps:
30.1
EXAMPLE 302- 2-(4-chlorophenyl)-1 H-imidazol-4-yl]-1 -[2-(methyloxy)ethyl]-1 H-benzimidazoleEtOH, H20Step 1 . [2-(methyloxy)ethyl](2-nitrophenyl)amine: 1 -fluoro-2-nitrobenzene (100 mg, 0.709 mmol) was dissolved in Ethanol (400 μΙ) and DIEA (371 μΙ, 2.126 mmol) was added and added to a microwave vial. 2-(methyloxy)ethanamine (53.2 mg, 0.709 mmol) was added and the vial was capped and heated at 150°C for 19 minutes. LCMS confirms complete conversion to the product. The solvent was removed and the product was carried on without further purification. Quantitative yield was assumed
References:
WO2011/123609,2011,A1 Location in patent:Page/Page column 30
1493-27-2
506 suppliers
$5.00/10g
109-85-3
264 suppliers
$10.00/1g
56436-24-9
8 suppliers
$309.00/1g
56436-25-0
12 suppliers
$45.00/10mg
7487-88-9
662 suppliers
$5.00/25g
1493-27-2
506 suppliers
$5.00/10g
109-85-3
264 suppliers
$10.00/1g
56436-24-9
8 suppliers
$309.00/1g
