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6273-94-5

N-Methyl-N-phenylpropenamide synthesis

7synthesis methods
-

Yield:6273-94-5 96%

Reaction Conditions:

Stage #1: N-acryloylanilinewith sodium hydride in tetrahydrofuran at 0; for 0.25 h;Inert atmosphere;
Stage #2: methyl iodide in tetrahydrofuran at 0 - 20; for 1 h;Inert atmosphere;

References:

Nascimento, Vinicius R.;Suenaga, Melissa L. S.;Andrade, Leandro H. [Organic and Biomolecular Chemistry,2020,vol. 18,# 28,p. 5458 - 5465]