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ChemicalBook CAS DataBase List N2-Cyclopropyl-4-Methyl-2,3-pyridinediaMine

N2-Cyclopropyl-4-Methyl-2,3-pyridinediaMine synthesis

2synthesis methods
284686-17-5 Synthesis
N-Cyclopropyl-4-Methyl-3-nitro-2-pyridinaMine

284686-17-5
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Yield:284686-18-6 83%

Reaction Conditions:

Stage #1: 2-(cyclopropylamino)-4-methyl-3-nitropyridinewith hydrogenchloride;tin(II) chloride dihdyrate;acetic acid in water at 20;
Stage #2: with sodium hydroxide in water; pH=12;Cooling with ice;

References:

Khunnawutmanotham, Nisachon;Chimnoi, Nitirat;Techasakul, Supanna;Thitithanyanont, Arunee;Saparpakorn, Patchreenart;Hannongbua, Supa;Choowongkomon, Kiattawee;Pungpo, Pornpan [Beilstein Journal of Organic Chemistry,2009,vol. 5,art. no. A36] Location in patent:supporting information; experimental part