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ChemicalBook CAS DataBase List Neutrophil Elastase Inhibitor

Neutrophil Elastase Inhibitor synthesis

1synthesis methods
50264-88-5 Synthesis
1H-INDAZOLE-3-CARBONITRILE

50264-88-5
127 suppliers
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1711-06-4 Synthesis
3-Methylbenzoyl chloride

1711-06-4
306 suppliers
$6.00/25g

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Yield: 22%

Reaction Conditions:

with triethylamine in dichloromethane at 0 - 20;

References:

Crocetti, Letizia;Schepetkin, Igor A.;Cilibrizzi, Agostino;Graziano, Alessia;Vergelli, Claudia;Giomi, Donatella;Khlebnikov, Andrei I.;Quinn, Mark T.;Giovannoni, Maria Paola [Journal of Medicinal Chemistry,2013,vol. 56,# 15,p. 6259 - 6272]