NSC 54274 synthesis
3synthesis methods
- Product Name:NSC 54274
- CAS Number:16350-59-7
- Molecular formula:C5H6N2O2S
- Molecular Weight:158.18
Yield:16350-59-7 64%
Reaction Conditions:
Stage #1: 5-iodouracilwith methylmagnesium chloride;lithium chloride in tetrahydrofuran at -20; for 0.333333 h;
Stage #2: with TurboGrignard in tetrahydrofuran at 20; for 1 h;
Stage #3: methanethiosulfonic acid S-methyl ester at -20 - 20;Further stages.;
References:
Kopp, Felix;Knoechel, Paul [Organic Letters,2007,vol. 9,# 9,p. 1639 - 1641]
