![](/CAS/GIF/66104-22-1.gif)
Pergolide synthesis
- Product Name:Pergolide
- CAS Number:66104-22-1
- Molecular formula:C19H26N2S
- Molecular Weight:314.49
![6-methylergoline-8beta-carboxylic acid](/CAS/GIF/5878-43-3.gif)
5878-43-3
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![Pergolide](/CAS/GIF/66104-22-1.gif)
66104-22-1
67 suppliers
$40.00/10 mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: sodium hydrogencarbonate / 1-methyl-pyrrolidin-2-one / 80 °C / Large scale
1.2: 65 °C / Large scale
1.3: 12 h / 75 °C / Large scale
2.1: pyridine / dichloromethane / 1 h / -5 °C / Inert atmosphere; Reflux; Large scale
2.2: 1 h / -5 °C / Inert atmosphere; Large scale
3.1: 1-methyl-pyrrolidin-2-one; dichloromethane / 20 °C / Inert atmosphere; Reflux; Large scale
3.2: 0 °C / Inert atmosphere; Large scale
References:
Cabri, Walter;Roletto, Jacopo;Olmo, Sara;Fonte, Piera;Ghetti, Paolo;Songia, Simonetta;Mapelli, Elio;Alpegiani, Marco;Paissoni, Paolo [Organic Process Research and Development,2006,vol. 10,# 2,p. 198 - 202]
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![METHYL MERCAPTAN](/CAS/GIF/74-93-1.gif)
74-93-1
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$454.02/5MG
![Pergolide](/CAS/GIF/66104-22-1.gif)
66104-22-1
67 suppliers
$40.00/10 mg
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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![Pergolide](/CAS/GIF/66104-22-1.gif)
66104-22-1
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$40.00/10 mg
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63719-21-1
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![PERGOLIDE MESYLATE INTERMEDIATE](/CAS/20211123/GIF/63719-21-1.gif)
63719-21-1
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![Pergolide](/CAS/GIF/66104-22-1.gif)
66104-22-1
67 suppliers
$40.00/10 mg
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5188-07-8
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![Pergolide](/CAS/GIF/66104-22-1.gif)
66104-22-1
67 suppliers
$40.00/10 mg