ChemicalBook CAS DataBase List Prostaglandin E1

Prostaglandin E1 synthesis

7synthesis methods

Product Name:Prostaglandin E1
CAS Number:745-65-3
Molecular formula:C20H34O5
Molecular Weight:354.49

2-Oxa-3-azabicyclo[2.2.1]heptane-5-heptanoic acid, 6-(hydroxymethyl)-3-phenyl-, methyl ester, (1R,4S,5R,6S)-rel-

125180-07-6
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745-65-3
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Yield:-

Steps:

Multi-step reaction with 5 steps
1: 93 percent / DMSO, (COCl)2 / CH₂Cl₂ / -60 °C
2: 92 percent / 1,2-dimethoxy-ethane / 0 °C
3: (S)-BINAL-H / tetrahydrofuran / -100 - -78 °C
4: 1.) m-CPBA, 2.) NH₄Cl, H₂O / 1.) CH₂Cl₂, 0 deg C
5: 72 percent / 0.1 M phosphate buffer / Baker's yeast, pH 7.0

References:

Hwu;Robl;Gilbert [Journal of the American Chemical Society,1992,vol. 114,# 8,p. 3125 - 3126]

3434-33-1
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745-65-3
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References

Prost-13-en-1-oic acid, 11,15-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9-hydroxy-, (9α,11α,13E,15S)-

1251949-12-8
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745-65-3
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References

2-Oxa-3-azabicyclo[2.2.1]heptane-5-heptanoic acid, 6-formyl-3-phenyl-, methyl ester, (1R,4S,5R,6R)-rel-

125180-08-7
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745-65-3
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References

2-Oxa-3-azabicyclo[2.2.1]heptane-5-heptanoic acid, 6-(3-oxo-1-octenyl)-3-phenyl-, methyl ester, [1α,4α,5β,6α(E)]- (9CI)

125180-09-8
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745-65-3
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$19.00/1mg

References

Prostaglandin E1 Related Search:

Folic acid Glycine Bromocyclopentane Stearic acid Cyclopentyl chloride Ethyl 2-(Chlorosulfonyl)acetate Citric acid Latanoprost 1-OCTENE Heptanoic acid