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ChemicalBook CAS DataBase List Spiro[isobenzofuran-1(3H),4'-piperidin]-3-one

Spiro[isobenzofuran-1(3H),4'-piperidin]-3-one synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: (i) nBuLi, THF, (ii) /BRN= 128556/, (iii) aq. HCl, CHCl3
2: H2 / Pd-C / ethanol / 20 h

References:

Marxer;Rodriguez;McKenna;Tsai [Journal of Organic Chemistry,1975,vol. 40,# 10,p. 1427 - 1433]

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