![](/CAS/GIF/2615-25-0.gif)
trans-1,4-Diaminocyclohexane synthesis
- Product Name:trans-1,4-Diaminocyclohexane
- CAS Number:2615-25-0
- Molecular formula:C6H14N2
- Molecular Weight:114.19
![1,4-CYCLOHEXANEDIAMINE](/CAS/GIF/3114-70-3.gif)
3114-70-3
196 suppliers
$12.00/1g
![trans-1,4-Diaminocyclohexane](/CAS/GIF/2615-25-0.gif)
2615-25-0
271 suppliers
$5.00/1g
![CIS-1,4-CYCLOHEXANEDIAMINE](/CAS/GIF/15827-56-2.gif)
15827-56-2
77 suppliers
$28.00/100mg
Yield:30 % de
Reaction Conditions:
with 1-methoxy-2-propanol;5% rhodium on activated aluminium oxide;sodium methylate at 200; under 90009 Torr; for 2 h;Inert atmosphere;Autoclave;Pressure;Temperature;
Steps:
1 Example 1
In a 500 mL autoclave, 100 g of 1,4-diaminocyclohexane (cis / trans form = 80/20, manufactured by Tokyo Chemical Industry Co., Ltd.), 100 g of propylene glycol monomethyl ether (PGME) 7.5 g of Ru catalyst ("AA-4501", 5% Ru alumina powder, manufactured by N. E-Chemcat Co., Ltd.) and 0.63 g of sodium methoxide (manufactured by Tokyo Chemical Industry Co., Ltd.) were charged, (N 2) gas (10 kgf / cm 3) was repeated three times, and the inside of the system was replaced with nitrogen gas.While stirring at a stirring speed of 300 rpm, a temperature The reaction was carried out for 2 hours under the condition of 200 ° C. and pressure (pressure of N 2 gas) of 12 MPa. After the reaction, the reaction mixture was cooled to room temperature and pressure filtered using a 0.2 μm membrane filter to remove the catalyst to obtain a filtrate. Analysis of the obtained filtrate by gas chromatography mass spectrometry (GC-MS) revealed that the proportion of cis isomer was 63.37 area%, the proportion of trans form was 34.7 area%, the other components (4-aminocyclo By-product such as hexanol) was 1.93 area%, and cis / trans form = 65/35.
References:
JP2015/13833,2015,A Location in patent:Paragraph 0062; 0073
![1,4-Cyclohexanediol](/CAS/GIF/556-48-9.gif)
556-48-9
301 suppliers
$6.00/5g
![trans-1,4-Diaminocyclohexane](/CAS/GIF/2615-25-0.gif)
2615-25-0
271 suppliers
$5.00/1g
![CIS-1,4-CYCLOHEXANEDIAMINE](/CAS/GIF/15827-56-2.gif)
15827-56-2
77 suppliers
$28.00/100mg
![p-Phenylenediamine](/CAS/GIF/106-50-3.gif)
106-50-3
604 suppliers
$17.00/25g
![trans-1,4-Diaminocyclohexane](/CAS/GIF/2615-25-0.gif)
2615-25-0
271 suppliers
$5.00/1g
![2,6-Dimethoxyhydroquinone](/CAS/GIF/15233-65-5.gif)
15233-65-5
83 suppliers
$45.00/100mg
![trans-1,4-Diaminocyclohexane](/CAS/GIF/2615-25-0.gif)
2615-25-0
271 suppliers
$5.00/1g
![CIS-1,4-CYCLOHEXANEDIAMINE](/CAS/GIF/15827-56-2.gif)
15827-56-2
77 suppliers
$28.00/100mg
![2,6-DIMETHOXY-1,4-BENZOQUINONE](/CAS/GIF/530-55-2.gif)
530-55-2
132 suppliers
$23.50/1g
![trans-1,4-Diaminocyclohexane](/CAS/GIF/2615-25-0.gif)
2615-25-0
271 suppliers
$5.00/1g
![CIS-1,4-CYCLOHEXANEDIAMINE](/CAS/GIF/15827-56-2.gif)
15827-56-2
77 suppliers
$28.00/100mg