ChemicalBook CAS DataBase List TRIETHYLAMINE HYDROBROMIDE

TRIETHYLAMINE HYDROBROMIDE synthesis

5synthesis methods

Product Name:TRIETHYLAMINE HYDROBROMIDE
CAS Number:636-70-4
Molecular formula:C6H16BrN
Molecular Weight:182.1

2576-47-8 Synthesis

2576-47-8
479 suppliers
$8.00/25g

555-16-8
544 suppliers
$5.00/5g

Ethanamine, 2-bromo-N-[(4-nitrophenyl)methylene]-

524678-17-9
0 suppliers
inquiry

636-70-4
122 suppliers
$36.22/100g

Yield:524678-17-9 80%

Reaction Conditions:

with triethylamine in dichloromethane;

Steps:

11.a a) Protection of 2-bromoethylammonium bromide

14 mmol (2.87 g) of 2-bromoethylammonium bromide 1 and 14 mmol (1.95 ml, 1.42 g) of triethylamine are dissolved with stirring in 100 ml of dichloromethane in a 150 ml two-necked flask. 10 mmol (1.51 g) of para-nitrobenzaldehyde 2 are added to the solution and the mixture is kept stirred overnight. [0201] The solvent is evaporated and the resulting yellow solid is taken up in 50 ml of dichloromethane and 50 ml of water. The organic phase is extracted with 3×25 ml of dichloromethane and washed with 3×25 ml of water, then dried over magnesium sulphate and concentrated under vacuum. 2.16 g of yellow solid 3 are obtained. The yield is 80%

References:

US2005/8568,2005,A1 Location in patent:Page 8