아레콜린
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아레콜린 속성
- 녹는점
- 171-175 °C
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- H2O: 0.1 g/mL, 투명, 무색
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 6.84(at 25℃)
- 색상
- 흰색에서 밝은 노란색
- Merck
- 14,778
- BRN
- 3914826
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. 솔루션이 안정적이지 않습니다. – 매일 신선하게 만드세요.
- InChI
- InChI=1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H
- InChIKey
- AXOJRQLKMVSHHZ-UHFFFAOYSA-N
- SMILES
- C1(C(=O)OC)=CCCN(C)C1.Br
- CAS 데이터베이스
- 300-08-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-23/24/25 | ||
| 안전지침서 | 45-38-36/37/39-28A | ||
| 유엔번호(UN No.) | 1544 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | QT2275000 | ||
| F 고인화성물질 | 8 | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29399990 | ||
| 독성 | LD50 par-rat: 270 mg/kg ABMGAJ 28,681,72 |
아레콜린 C화학적 특성, 용도, 생산
화학적 성질
WHITE FINE POWDER용도
Arecoline is a muscarinic acetylcholine receptor agonist. Arecoline induces ADP ribosylation of histones and chromatid relaxation in spleen and bone marrow cells. In a study, a controlled trial involving 122 dogs experimentally infected with Echinococcus일반 설명
Arecoline is an alkaloid obtained from theseeds of the betel nut (Areca catechu). For many years, nativesof the East Indies have consumed the betel nut as asource of a euphoria-creating substance.Safety Profile
Poison by parenteral,subcutaneous, and intravenous routes. When heated todecomposition it emits very toxic fumes of HBr and NOx.Toxicology
Eighty rats were randomly divided into four groups: a high-dose group (1000 mg/kg), a medium-dose group (200 mg/kg), a low-dose group (100mg/kg), and a blank control group. The doses were administered daily via gastric lavage for 14 consecutive days. There were no significant differences in the low-dose Arecoline hydrobromide (Ah) group compared to the control group (P>0.05) with regard to body weight, organ coefficients, hematological parameters, and histopathological changes. In this study, the rats in the high-dose group exhibited clear inhibitory effects on blood biochemical parameters, including ALT, TP, and BUN levels. It was demonstrated that the toxicity reaction was intensified at the higher dosage, and clinical dosing should occur within a safe dosage range. With a continuous increase in the Ah dose, organ damage was aggravated, with different degrees of congestion, degeneration, and necrosis observed. The results accurately reflected the liver and kidney changes, whereas the results for the changes in the lung were poor. Hence, a long-term, continuous high dose of Ah was toxic[4].아레콜린 준비 용품 및 원자재
원자재
준비 용품
아레콜린 공급 업체
글로벌( 437)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 |
gao490372054@gamil.com | China | 1250 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-19164747840 +86-13119157289 |
13119157289@163.com | China | 2971 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12471 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 |
kyra@quanjinci.com | China | 1534 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 18229 | 58 |
| Shandong Juchuang Chemical Co., LTD | +undefined15030412209 |
admin@juchuangchem.com | China | 387 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 |
sales05@airuikechemical.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |