| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester
CAS:188404-10-6
Package:50Mg,5Mg
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| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:MAFP;(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenyl-Methylesterphosphonofluoridicacid
CAS:188404-10-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Shanghai TaoSu Biochemical Technology Co., Ltd.
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| Tel: |
021-33632979 |
| Email: |
info@tsbiochem.com |
| Products Intro: |
Product Name:(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester
CAS:188404-10-6
Purity:90% Package:5Mg;50Mg;;
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| Product Name: | MAFP | | Synonyms: | 5Z,8Z,11Z,14Z-EICOSATETRAENYL-PHOSPHONOFLUORIDIC ACID, METHYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENYL-METHYL ESTER PHOSPHONOFLUORIDIC ACID;MAFP;MAPF;METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENYL ESTER PHOSPHONOFLUORIDIC ACID METHYL ACETATE;METHYL ARACHIDONYL FLUOROPHOSPHONATE;METHYLPHOSPHONOFLUORIDIC ACID 5,8,11,14-EICOSATETRAENYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenylmethylester | | CAS: | 188404-10-6 | | MF: | C21H36FO2P | | MW: | 370.48 | | EINECS: | 201-185-2 | | Product Categories: | Cannabinoid receptor;Fatty Acid Derivatives & Lipids, inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 188404-10-6.mol |  |
| Boiling point | 455.3±34.0 °C(Predicted) | | density | 0.960±0.06 g/cm3(Predicted) | | RTECS | TA8108000 | | Fp | -16 °C | | storage temp. | -70°C | | solubility | DMF: 3 mg/ml; DMSO: 3 mg/ml; Ethanol: 3.5 mg/ml; Ethanol:PBS (pH 7.2) 1:1: .5 mg/ml; PBS (7.2): <1 mg/ml (colloidal suspension | | form | methyl acetate solution | | Sensitive | Air Sensitive |
| Uses | (all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester, is a cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors. | | Definition | ChEBI: Methyl Arachidonyl Fluorophosphonate is a phosphonic ester. | | Biological Activity | Potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH, anandamide amidase), the enzyme responsible for anandamide hydrolysis (IC 50 = 2.5 nM). Also binds irreversibly to CB 1 receptors (IC 50 = 20 nM). | | Biochem/physiol Actions | MAFP is a selective, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic phospholipase A2, but not secretory phospholipase A2. MAFP is also a potent acetylcholinesterase inhibitor. |
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