ChemicalBook CAS DataBase List 1H-Imidazole-4-carboxylic acid

1H-Imidazole-4-carboxylic acid synthesis

10synthesis methods

Product Name:1H-Imidazole-4-carboxylic acid
CAS Number:1072-84-0
Molecular formula:C4H4N2O2
Molecular Weight:112.09

23785-21-9 Synthesis

23785-21-9
245 suppliers
$6.00/250mg

1072-84-0
368 suppliers
$10.00/1g

Yield:1072-84-0 92.49%

Reaction Conditions:

with potassium hydroxide at 30;Temperature;Concentration;

Steps:

5.3 The third step: Preparation of lH-imidazole-4-carboxylic acid
The mass ratio of 1 H-imidazole-4-carboxylic acid ethyl ester to potassium hydroxide solution was 1: 2.2, the reaction temperature was 30 After the completion of the reaction, the sulfuric acid solution is added, the pH is adjusted to 1, and the crude product is recrystallized from the recrystallization solvent to obtain 1H-imidazole-4-carboxylic acid.

References:

ITIC Medchem(Suzhou) Co., Ltd.;Hu, Haiwei;Ding, Jing;Yan, Yongping;Zheng, Hui;Yan, Hui CN105693619, 2016, A Location in patent:Paragraph 0010; 0088; 0089

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822-36-6 Synthesis