Erdafitinib can be used to treat urothelial cancer
Erdafitinib, also known as JNJ-42756493, is a first-in-class pan-fibroblast growth factor receptor (FGFR) kinase inhibitor discovered by Astex Pharmaceuticals and Janssen.
Jan 19，2024 Inhibitors
Types and properties of Glass
As a general rule, glasses are amorphous inorganic solids usually made of silicates, but other inorganic or organic compounds can exhibit a vitreous structure (e.g., sulfides, polymers)
Jan 19，2024 API
Q：What is Bicinchoninic Acid Protein Assay?
A：Bicinchoninic acid (BCA; 2,2'-Bicinchoninic Acid) assay or Smith assay is a copper-based colorimetric assay for total protein quantification.
Jan 19，2024 Organic reagents
Acephate: toxic effects, physicochemical and microbial degradation
Acephate has toxic effects on organisms, causing DNA damage, and impaired immune response. physicochemical and microbial degradation show promise in reducing its toxicity.
Jan 19，2024 API
Microbiological Biosynthesis of Polyglutamic Acid and Applications in the Food and Drug Delivery Industries
Polyglutamic acid is challenging to synthesize and has diverse applications in food and drug delivery industries due to its unique properties and potential benefits.
Jan 19，2024 API
Side effects and toxicity of Ethylene thiourea in humans
Ethylene thiourea (ETU) is an imidazolidine compound with the appearance of a white crystalline solid, produced by the action of ethylenediamine on carbon disulphide in hydroalcohol.
Jan 18，2024 API
How to synthesize Entrectinib
Entrectinib is an orally available, CNS-active, selective inhibitor of the tyrosine kinases tropomyosin receptor kinase (Trk) A/B/C, anaplastic lymphoma kinase (ALK), and c-ros oncogene 1 (ROS1).
Jan 18，2024 Biochemical Engineering
The uses of 2',7'-Dichlorofluorescein
DCF is used directly, there is a decline in fluorescence in the presence of ROS. Hence, DCFH2-DA (not DCF) should be used to indicate ROS generation.
Jan 18，2024 Analytical Chemistry
Difelikefalin: Synthesis and Introduction
Difelikefalin is synthesised using piperidine amino acid as a raw material by chemical reaction.
Jan 18，2024 Drugs
Finerenone: Synthesis and Introduction
Finerenon, or BAY94- 8862, is a non-steroidal mineralocorticoid receptor (MR) antagonist approved by the USFDA in July 2021 and the EMA and the Japanese Ministry o
Jan 18，2024 Drugs