The uses of D-Glucosamine hydrochloride.
D-glucosamine hydrochloride is an endogenous amino monosaccharide synthesized from glucose that is useful in the treatment of joint diseases in both humans and animals.
Jan 3，2024 API
Salcaprozate Sodium Facilitates Oral Delivery of Low-Permeability Drugs
Salcaprozate sodium enhances API absorption, potentially improving drug efficacy and bioavailability. Extensively studied in oral formulations, it is deemed safe by the FDA.
Jan 3，2024 API
Understanding the Applications and Safety Considerations of (2-Bromoethyl)benzene
(2-Bromoethyl)benzene is a moderately lipophilic compound used in pharmaceuticals and fine chemicals. It has limited solubility in water, acute toxicity, and can pose occupational exposure risks.
Jan 3，2024 API
4,4'-Methylenedianiline enables eco-friendly polyurea polymer synthesis
4,4'-Methylenedianiline is a versatile reactant and catalyst with applications in organic synthesis. However, its release poses environmental hazards, requiring proper handling.
Jan 3，2024 API
Microbial Fermentation and Biosynthesis Pathways: L-Malic Acid Production in Multiple Industries
L-Malic acid is produced through microbial fermentation or chemical conversion, with glucose or fumaric acid as substrates. Enzyme expression and pH regulation are crucial for optimizing biosynthesis.
Jan 3，2024 API
An irreversible EGFR/HER2 dual tyrosine kinase inhibitor: Pyrotinib Maleate
Pyrotinib, an irreversible EGFR/HER2 dual tyrosine kinase inhibitor used for treating HER2-positive breast cancer, is primarily metabolized by cytochrome P450 (CYP)3A4 isozyme.
Jan 2，2024 Inhibitors
How to synthesize Lorlatinib?
Lorlatinib is an oral small molecule inhibitor of anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (ROS1) kinase developed by Pfizer for the treatment of ALK-positive non-small cell lung cancer.
Jan 2，2024 Inhibitors
The Synthetic method of Larotrectinib (LOXO-101)
Larotrectinib (LOXO-101) is the first highly potent and selective small molecule ATP competitive inhibitor of all three TRK kinases (TRKA, TRKB, and TRKC) to enter clinical development.
Jan 2，2024 API
Properties and Applications of Silicone Oil
Silicone oils are constituted of a linear chain of siloxane repeating units (–Si–O) and a variety of side chains (radical side groups).
Jan 2，2024 API
Sodium carbonate: Applications and Security
Sodium carbonate is the disodium carbonate salt with an alkaline base. It is widely used in industry.
Jan 2，2024 API