| Identification | More | [Name]
Zineb | [CAS]
12122-67-7 | [Synonyms]
((1,2-ethanediylbis(carbamodithioato))(2-))-zin
((1,2-ethanediylbis(carbamodithioato))(2-))zinc
(ethylenebis(dithiocarbamato))-zin
1,2-ethanediylbis(carbamodithioato)(2-)-s,s’-zinc
1,2-ethanediylbis-carbamodithioicacizincsalt
aphytora
aspor
asporum
bercema
blightox
blizene
carbadine
carbamodithioicacid,1,2-ethanediylbis,zincsalt
caswellnumber930
chemzineb
cineb
crystalzineb
cynkotox
daisen
deikusol | [EINECS(EC#)]
235-180-1 | [Molecular Formula]
C4H6N2S4Zn | [MDL Number]
MFCD00067266 | [Molecular Weight]
275.75 | [MOL File]
12122-67-7.mol |
| Chemical Properties | Back Directory | [Description]
Zineb is a light-coloured powder/crystal and insoluble in water. Zineb is one of the nonsystemic
(surface-acting) fungicides of the group ethylenebisdithiocarbamates (EBDCs).
Zineb is a polymer of ethylene (bis)thiocarbamate units linked with zinc and used for the
control and prevention of crop damage in the field and also to protect harvested crops from
deterioration during storage or transport. Zineb was used to protect fruit and vegetable
crops from a wide range of foliar and other diseases. It was available in the United States
as wettable powder and dust formulations. Zineb can be formed by combining nabam and
zinc sulphate in the spray tank. | [Appearance]
Light-tan solid. Insoluble in water; soluble
in pyridine; decomposes on heating. | [Melting point ]
157°C (rough estimate) | [vapor pressure ]
<1x l0-5 at 20 °C | [Fp ]
90℃ | [storage temp. ]
2-8°C | [density ]
1.74 g/cm3 | [form ]
Water-Insoluble Powder | [Water Solubility ]
ca.10 mg l-1 (room temperature) | [Merck ]
13,10220 | [BRN ]
4165797 | [Contact allergens]
Zineb is a pesticide of the dithiocarbamate group.
Sensitization can occur in gardeners and florists. | [InChIKey]
AMHNZOICSMBGDH-UHFFFAOYSA-L | [CAS DataBase Reference]
12122-67-7(CAS DataBase Reference) | [IARC]
3 (Vol. 12, Sup 7) 1987 | [EPA Substance Registry System]
12122-67-7(EPA Substance) |
| Hazard Information | Back Directory | [Definition]
ChEBI: A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU. | [Uses]
Agricultural fungicide. | [General Description]
An off-white powder. Used as a fungicide. | [Reactivity Profile]
ZINEB(12122-67-7) is a zinc salt of a dithiocarbamic acid. May generate flammable gases with aldehydes, nitrides, and hydrides. Incompatible with acids, peroxides, and acid halides. | [Air & Water Reactions]
Decomposes gradually, accelerated by exposure to air, moisture, and heat. Insoluble in water. Thio and dithiocarbamates slowly decompose in aqueous solution to form carbon disulfide and methylamine or other amines. Such decompositions are accelerated by acids. | [Fire Hazard]
Flash point data for this chemical are not available, but ZINEB is probably combustible. | [Chemical Properties]
Light-tan solid. Insoluble in water; soluble
in pyridine; decomposes on heating. | [Hazard]
Toxic by inhalation and ingestion; irritant
to eyes and mucous membranes. Questionable carcinogen. | [Metabolic pathway]
Zineb and other alkylenebis( dithiocarbamate) fungicides are degraded
and metabolised via a common pathway. The primary degradation
reaction of zineb in water, soil, plants and animals involves the initial
dissociation of the metal complex and decomposition to numerous degradation
products including ethylenethiourea (ETU) and ethyleneurea (EU)
as major products (Scheme 1). | [Purification Methods]
Crystallise this herbicide several times from hot toluene or from hot CHCl3 by addition of EtOH. It is a skin irritant. [Beilstein 4 III 149, 4 IV 234.] | [Degradation]
[14C-ethylene]Zineb(1) was decomposed mainly to ETU (2) in an aqueous
suspension after 14 days via the 5,6-dihydro-3H-imidazo[2,1-c]-1,2,4-
dithiazole-3-thione (3) intermediate (Vonk, 1976). In dilute alkaline solution
and in the presence of light, heat and moisture, zineb decomposed
rapidly to compound 3 (Marshall, 1978). ETU (2) in aqueous solutions
was further converted into 2-imidazoline (4) and EU (5) (kaars Sijpesteijn
and Vonk, 1974). Zineb decomposed in sterile marine culture medium to
yield ETU (2) and compound 3. In the presence of copper, an additional
degradation product, ethylene diisothiocyanate (6), was also observed
(Hunter and Evans, 1991). | [Toxicity evaluation]
Zineb has a low mammalian toxicity however, it may cause adverse reproduction/developement effects if ingested. It is moderately toxic to most fauna and flora.
|
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R37:Irritating to the respiratory system.
R43:May cause sensitization by skin contact. | [Safety Statements ]
S8:Keep container dry .
S24/25:Avoid contact with skin and eyes .
S46:If swallowed, seek medical advice immediately and show this container or label . | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3 | [RTECS ]
ZH3325000 | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29309090 | [Hazardous Substances Data]
12122-67-7(Hazardous Substances Data) | [Toxicity]
LD50 orally in rats: >5000 mg/kg (Gaines) |
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