HA-1004 (hydrochloride)

92564-08-4

CAS-Nr.: 92564-08-4

Englisch Name:: HA-1004 (hydrochloride)

Synonyma:

CBNumber:: CB04814674

Summenformel:: C12H16ClN5O2S

Molgewicht:: 329.8

MOL-Datei:: 92564-08-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 4

HA-1004 (hydrochloride) Eigenschaften

storage temp.: Store at -20°C

Löslichkeit: DMF:2.0(Max Conc. mg/mL);5.46(Max Conc. mM)
DMSO:3.0(Max Conc. mg/mL);8.19(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);13.65(Max Conc. mM)

Sicherheit

HA-1004 (hydrochloride) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (K_is = 1.4 and 2.3 μM, respectively). It also inhibits PKC and blocks intracellular calcium mobilization. HA-1004 induces relaxation of isolated rabbit aortic strips precontracted with histamine, serotonin , A23187 , angiotensin II , or prostaglandin F_2α (; EC₅₀s = 0.32-0.63 μM), as well as phenylephrine (Item Nos. 18619 | 17205) with or without calcium (EC₅₀s = 2.3 and 0.5 μM, respectively). It also inhibits histamine-induced bronchoconstriction in guinea pigs without affecting blood pressure when administered intratracheally at a dose of 0.1 mg per animal.

HA-1004 (hydrochloride) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

HA-1004 (hydrochloride) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 4)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28118	58

92564-08-4