HA-1004 (hydrochloride)
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HA-1004 (hydrochloride) 속성
- 저장 조건
- Store at -20°C
- 용해도
- DMF:2.0(Max Conc. mg/mL);5.46(Max Conc. mM)
DMSO:3.0(Max Conc. mg/mL);8.19(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);13.65(Max Conc. mM)
안전
HA-1004 (hydrochloride) C화학적 특성, 용도, 생산
개요
HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively). It also inhibits PKC and blocks intracellular calcium mobilization. HA-1004 induces relaxation of isolated rabbit aortic strips precontracted with histamine, serotonin , A23187 , angiotensin II , or prostaglandin F2α (; EC50s = 0.32-0.63 μM), as well as phenylephrine (Item Nos. 18619 | 17205) with or without calcium (EC50s = 2.3 and 0.5 μM, respectively). It also inhibits histamine-induced bronchoconstriction in guinea pigs without affecting blood pressure when administered intratracheally at a dose of 0.1 mg per animal.HA-1004 (hydrochloride) 준비 용품 및 원자재
원자재
준비 용품
HA-1004 (hydrochloride) 공급 업체
글로벌( 4)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| TargetMol Chemicals Inc. | 15002134094 |
marketing@targetmol.cn | China | 28118 | 58 |