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HA-1004 (hydrochloride)

HA-1004 (hydrochloride) Structure
HA-1004 (hydrochloride) structure
CAS No.
92564-08-4
Chemical Name:
HA-1004 (hydrochloride)
Synonyms
CBNumber:
CB04814674
Molecular Formula:
C12H16ClN5O2S
Molecular Weight:
329.8
MDL Number:
MOL File:
92564-08-4.mol
Last updated:2023-05-21 10:59:17
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HA-1004 (hydrochloride) Properties

storage temp. Store at -20°C
solubility DMF:2.0(Max Conc. mg/mL);5.46(Max Conc. mM)
DMSO:3.0(Max Conc. mg/mL);8.19(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);13.65(Max Conc. mM)

HA-1004 (hydrochloride) price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010558 HA-1004 (hydrochloride) 92564-08-4 5mg $54 2022-04-27 Buy
Cayman Chemical 10010558 HA-1004 (hydrochloride) 92564-08-4 10mg $96 2022-04-27 Buy
Product number Packaging Price Buy
10010558 5mg $54 Buy
10010558 10mg $96 Buy

HA-1004 (hydrochloride) Chemical Properties,Uses,Production

Description

HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively). It also inhibits PKC and blocks intracellular calcium mobilization. HA-1004 induces relaxation of isolated rabbit aortic strips precontracted with histamine, serotonin , A23187 , angiotensin II , or prostaglandin F2α (; EC50s = 0.32-0.63 μM), as well as phenylephrine (Item Nos. 18619 | 17205) with or without calcium (EC50s = 2.3 and 0.5 μM, respectively). It also inhibits histamine-induced bronchoconstriction in guinea pigs without affecting blood pressure when administered intratracheally at a dose of 0.1 mg per animal.

HA-1004 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

HA-1004 (hydrochloride) Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28118 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
TargetMol Chemicals Inc. 58
92564-08-4