SEA-0400 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
SEA0400 is a selective inhibitor of the Na
+/Ca
2+ exchanger (IC
50s = 5, 8.3, and 33 nM for inhibiting Na
+-dependent Ca
2+ uptake in rat astrocyte, microglia, and cortical neuron cell lines, respectively). It is reported to prevent dopaminergic neurotoxicity in an MPTP mouse model of Parkinson''s disease and to attenuate reperfusion injury in both
in vitro and
in vivo cerebral ischemic models.
Verwenden
SEA 0400 is a novel and selective inhibitor of Na+-Ca2+ exchanger.
SEA-0400 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte