SEA-0400 化学特性,用途語,生産方法
説明
SEA0400 is a selective inhibitor of the Na
+/Ca
2+ exchanger (IC
50s = 5, 8.3, and 33 nM for inhibiting Na
+-dependent Ca
2+ uptake in rat astrocyte, microglia, and cortical neuron cell lines, respectively). It is reported to prevent dopaminergic neurotoxicity in an MPTP mouse model of Parkinson''s disease and to attenuate reperfusion injury in both
in vitro and
in vivo cerebral ischemic models.
使用
SEA 0400 is a novel and selective inhibitor of Na+-Ca2+ exchanger.
SEA-0400 上流と下流の製品情報
原材料
準備製品